Before the age of refrigeration, Russians had a peculiar method for keeping milk fresh: they would drop live brown frogs into their milk buckets! This bizarre tradition was believed to prevent spoilage, though the reasoning behind it remained a mystery. Surprisingly, recent scientific investigations revealed that this amphibian trick was more than just folklore.
Scientists explored the chemistry behind this practice and found that the frog’s skin secretes a special “frog goo” rich in powerful antibacterial and antifungal peptides. Albert Lebedev, a scientist from Moscow State University, explains that these chemicals are “enormously active,” and his team has identified 76 distinct peptides within the frog’s slimy coating. This discovery suggests potential for developing new antibiotics and medicines.
To safely collect the goo for research, scientists used electrodes to stimulate the frog’s skin, ensuring minimal harm to the creature. Interest from major pharmaceutical companies is growing, as these natural compounds could lead to innovative treatments. However, transforming these natural substances into effective medications is a complex process that can take years, if not decades.
Next time you pour a glass of milk, remember this quirky solution from the past and the surprising science behind it. For more details on Lebedev’s findings, check out their study in the Journal of Proteome Research 👉🏻 Read the study here.